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Biotech startupSynFlorabrought an enticing sales pitch for a new eccentric of cutis treatment engineering to 4YFN at the MWC tradeshow in Barcelona this hebdomad . The Spanish startup , a twirl - off out of Pompeu Fabra University whose three co - founding father all have PhDs , is working to amend understanding of the skin ’s microbiome and engineer skin microbes with the goal of enable more targeted and novel cure .
The introductory idea is to deliver treatments in a deeper way than locally applied creams , such as is the typeface with current - gen “ fighting ” skin care product — but also to plan and engineer a wider cooking stove of treatments by using biotech methods to harness bacteria to deliver targeted curative .
“ We are creating a nucleotide of a newfangled hide product which is not anymore just mote , which ca n’t go in the tegument because they ’re topically applied — it ’s really like a molecular political machine , ” says co - founder and CEO Nastassia Knödlseder . “ A bacterium which can move inside the hair follicle , like deep inside the skin , and produce new [ effects ] . ”
The team ’s early enquiry “ cogent evidence of conception ” work is focus on acne — and it ’s late published apaperon its experimental treatment rescue approach in the journal Nature Biotechnology ( on a test of a “ sebum modulator ” in an engineered skin germ in mice ) — but they envisage the overture being apply to take on a much wide cooking stove of issues , include thing that range well beyond what we might consider skincare .
possible use cases they mention could admit mosquito distasteful or fat loss ( a cream for making cellulite disappear anyone ? ) , per Knödlseder , or even vaccines and anti - inflammatory treatment .
“ We have the potential triggering the immune system or create vaccines against melanoma , for example , ” she suggest . “ We have the hypothesis of the production of anti - inflammatory molecules . ”
“ We see this really like as a chopine , ” she adds , confirming the squad has letters patent for dissimilar indications of the technology and for the political program itself . “ We really do n’t require to limit to one use suit . ”
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SynFlora is still at an former microscope stage — they ’re in the process of raising a seed circular , per Knödlseder — and will patently want to satisfy regulators of the base hit and efficaciousness of their novel bioengineered mechanics for delivering therapeutic deeply into the dermis before the technical school will be able to turn over consumers .
But the co - founder intimate they could be between one to three years away from their novel system powering a new generation of cutis - delivered therapeutics .
